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Data-Driven Innovation

性奴调教 research institutes leverage data to combat local and global challenges.

Three researchers from the 性奴调教 Geospatial Institute

Sandoval , Sagan and Shacham  are researchers at the 性奴调教 Geospatial Institute (Geo性奴调教). Photo by Steve Dolan

Researchers at 性奴调教 continually generate new ideas, paradigms and discoveries. And while news articles on these advances convey outcomes, they rarely shed light on the processes researchers used to identify problems or devise solutions.

Often, the painstaking practice involves sifting through mounds of data, looking for trends, finding patterns and leveraging that information for innovation. Two research institutions established by 性奴调教 are accelerating this data-mining process by developing new tools to gather information and novel methods to crunch the scientific data, which researchers are using to predict climate change, track infections and combat the opioid addiction crisis.

The 性奴调教 Advanced HEAlth Data (AHEAD) Research Institute and the 性奴调教 Geospatial Institute (Geo性奴调教) were created in 2018 with seed money from the Big Ideas competition designed to foster collaborative projects and cement 性奴调教鈥檚 reputation as a destination for training, research and discovery. The institutes also provide undergraduate and graduate students with opportunities to work with researchers and experience the impact of 性奴调教鈥檚 research worldwide.

AHEAD

With the shift to electronic medical records (EMR), the amount of digital patient health care data has increased exponentially, and Dr. Jeffrey Scherrer (Grad PH 鈥04) believes that buried within this data is information that can transform medical care and improve patient care.

Scherrer is senior director of research with 性奴调教鈥檚 AHEAD Institute, a comprehensive center for data-driven innovation and research aimed at improving individual and population health. The institute鈥檚 multi-disciplinary faculty, doctoral students, and experts in statistics and research methodology help investigators formulate research questions and analyze the massive amounts of data captured in electronic medical records. Data points are de-identified before researchers access them.

AHEAD researchers work with a variety of disciplines and use advanced analytic methods, predictive modeling and machine learning to explore such areas as pediatric otolaryngology, neurological cancers, infection control and hospital readmissions.

Scherrer and his colleagues used analysis of existing data from national data banks to study the prescribing behaviors of physicians before and after the Centers for Disease Control and Prevention issued opioid prescribing guidelines in 2016. By analyzing tens of thousands of electronic health data records across the United States, researchers learned what types of opioids patients were prescribed, why, how long they were prescribed and what types of specialists patients saw.

Two researchers from 性奴调教's AHEAD Institute

Hinyard and Scherrer Photo by Steve Dolan

鈥淏ecause we had access to existing historical data, we quickly were able to publish three papers in high-profile journals that documented what was happening,鈥 said Scherrer, professor of family and community medicine.

鈥淢any studies about provider-prescribing behaviors have relied on surveys and are limited by social desirability and recall. The information often was biased and not truly representative. Now, we have real-world information.鈥 

Mining for Research Gold

Scherrer also said access to existing data is a tremendous help for researchers and students who want to explore questions with minimal funding before pursuing larger grants. A 性奴调教Care endocrinologist, for example, suspected patients with lower socioeconomic status did not appear to have the same access to insulin pumps and continuous glucose monitoring as patients with higher insurance status.

The clinician turned to AHEAD experts and learned her observations were more than anecdotal. Nationwide, patients with lower socioeconomic status were not using the diabetes technology as often as other patients. This led to ongoing studies exploring whether the patients with greater access to the tools have better outcomes, and whether physicians are offering the tools, but patients are not using them.

鈥淲e鈥檝e collected data for years, but until the last few decades we lacked the capacity to use that data for anything actionable,鈥 said Dr. Leslie Hinyard (Grad PH 鈥08), associate professor and chairperson of the Department of Health and Clinical Outcomes Research, and director of AHEAD. 鈥淲e now have the computing power and methods to take health information and use it to understand who is getting access to what care and where, and whether what we鈥檙e doing is working, all without collecting new data. It鈥檚 more efficient and less expensive.鈥

Hinyard said no other institute in the St. Louis region offers the comprehensive research infrastructure provided by AHEAD, which is committed to addressing health care issues that disproportionally affect poor and underserved communities. She said AHEAD is primed to be a leader in data analytics because 性奴调教 has all the right people in all the right places.

鈥淲e have medical school faculty posing the clinical questions, public health faculty with public health expertise, and computer science faculty and students helping us develop the software we need to do what we do,鈥 Hinyard said. 鈥淚 love that we can work together and analyze existing information to use as a jumping-off point for change.鈥

The AHEAD Institute was recognized for its scientific excellence when it was invited to join the Health Care Systems Research Network, the nation鈥檚 preeminent source of population-based research. This put 性奴调教 in the company of approximately 20 other leading health care systems throughout the country, including Kaiser Permanente, Harvard Pilgrim Health Care and the Henry Ford Health Systems. AHEAD also is distinguished by its partnership with the SSM Health system and the 性奴调教Care Physician Group, giving researchers comprehensive, de-identified data about patient care in the Midwest.

Geo性奴调教

Before COVID-19, it took Dr. Enbal Shacham, professor of public health, a couple of minutes to explain to a layperson her research with geospatial science technology. Now, most people need no explanation. The outbreak demonstrated clearly why location matters when tracking and mitigating an infectious disease.

Shacham is associate director of Geo性奴调教, which has been in high gear for the past two years using geographic information systems, remote sensing and GPS to create maps and models of the coronavirus outbreak. Information gleaned from geospatial technology fuels the brightly colored dashboards found on websites and television programs with real-time confirmed cases of COVID-19, death rates, hot spots and vaccination rates.

鈥淕eospatial science is invaluable during a pandemic like this,鈥 Shacham said. 鈥淲e鈥檙e able to see human behaviors and patterns like never before. And the data we collect will inform more effective public health directives and keep more people safe.鈥

Geo性奴调教 researchers have been tracking COVID infection rates in nursing homes and airports, as well as factors related to people鈥檚 mobility following the implementation and lifting of stay-at-home orders. They studied mask mandates in five counties in the St Louis region 鈥 two with mask mandates, three without. 性奴调教 researchers found that infection rates dropped approximately 40% in a six-month period in the counties with the mask mandates compared to the counties without.

Using anonymized cellphone data, 性奴调教 researchers also found that when one county closed bars and indoor dining, some people in that county traveled to neighboring countries with no restrictions and spiked infection rates there.

鈥淧revious research was limited to home and work addresses, so public health officials did a lot of guessing and estimating about movement,鈥 Shacham said. 鈥淲hat鈥檚 amazing about geospatial science is we can supplement public health knowledge with this non-traditional public health data to better understand the social and physical environments people encounter daily. This leads to better interventions with infectious diseases as well as chronic diseases.鈥

Geo性奴调教 researchers, for example, are collaborating with an insurance provider in southern California to track air quality in two large counties. Researchers created an algorithm that sends text messages to parents of children with asthma when the air quality is poor and reminds them to have their children carry inhalers or other medications.

Their reach is global. Geo性奴调教 researchers are working with the St. Louis Zoo and organizations in Kenya to follow the movements of dromedary camels. Dromedary camels are important reservoir hosts of various coronaviruses that cause human infections, including Middle East respiratory syndrome coronavirus (MERS-CoV).

Field of Dreams

Public health is only one focus under the Geo性奴调教 umbrella.

Collaborating with faculty and national specialists in virology, engineering, computer science, sociology and medicine, institute researchers have dozens of projects underway in such areas as climate change; crime pattern analysis; disaster preparedness and response; sex trafficking; and economic development and social instability.

Geo性奴调教 has partnerships with major players in the geospatial community including the National Geospatial Intelligence Agency (NGA) headquartered in St. Louis, Boeing, Ameren and Enterprise.

Dr. Vasit Sagan, associate professor of geospatial science and director of Geo性奴调教, said the University has invested significant capital and talent to develop 性奴调教 and the city as a national hub for geospatial research. The Geo-Resolution 2021 conference sponsored by 性奴调教 and the NGA represents one such investment and highlights 性奴调教鈥檚 contribution to the growth of the regional geospatial ecosystem.

Sagan鈥檚 work focuses on improving crop productivity and food security. He uses drones, sensors and satellite imagery to monitor the impact of climate change, water supply, fertilization and other influences on sorghum and soybean crops.

鈥淲hat鈥檚 exciting is that I can use the geospatial data we collect and create something as simple as a color-coded map to help a farmer improve yield, not just in my community but across the globe,鈥 said Sagan, whose research could lead to a doubling of crop yields over the next 30 years.

In addition to fostering collaboration with researchers and partnering with stakeholders, Geo性奴调教 is developing new degree programs in the multi-billion-dollar field of geospatial science and creating opportunities for 性奴调教 students to engage in geospatial research. Students formed a Geo性奴调教 student organization this year.

Dr. Ness Sandoval, professor of sociology, and associate director of Geo性奴调教, specializes in geospatial statistics, which he uses to help students visualize neighborhoods.

鈥淎 lot of students want to understand their own neighborhoods. What do we know about immigration or what do we know about racial segregation? How do these patterns start?鈥 Sandoval said. 鈥淚t鈥檚 an eye-opener because they鈥檙e like, 鈥楩inally, I have objective evidence of my personal story.鈥欌

Researchers believe 性奴调教 is uniquely suited to be a leader in the geospatial research community because the University places the utmost importance on the ethical dimensions of geospatial technologies.

While geospatial mapping technologies have tremendous potential for good, without ethical reflection the same technologies can cause harm. Fears exist that the massive amount of data collected by satellites, street cameras and people who use cellphones or fitness devices may be used to invade the privacy of individuals and groups.

Geo性奴调教 assembled the Geospatial Ethics Research and Practice Group to scrutinize geospatial technologies and practices and make certain they are consistent with 性奴调教鈥檚 commitment to justice and the common good. The group is led by Shacham and Michael Rozier, S.J. (A&S 鈥03), assistant professor of health management and policy and EthicalGEO Fellow of the American Geographical Society. Robert Cardillo, former director of the National Geospatial Intelligence Agency and distinguished geospatial fellow at 性奴调教, also is a group member. 

鈥 By Marie Dilg

Universitas, the award-winning alumni magazine of 性奴调教, is distributed to 性奴调教 alumni, parents and benefactors around the world. The magazine includes campus news, feature stories, alumni profiles and class notes, and has a circulation of 129,300.